El recuento celular es un paso crítico en muchas aplicaciones de ciencias biológicas, incluidas la terapia celular, la producción biofarmacéutica y la investigación avanzada. La determinación precisa de la concentración, el tamaño y la viabilidad de las células es esencial para garantizar resultados experimentales confiables y la consistencia del proceso.
Sin embargo, los métodos de recuento manual tradicionales suelen consumir mucho tiempo, ser subjetivos y propensos a la variabilidad, mientras que los sistemas automatizados convencionales pueden tener dificultades con tipos celulares y condiciones complejas. Los laboratorios modernos requieren una solución que sea rápida, precisa y consistente en diversas aplicaciones.
Características imprescindibles a considerar:
- Alta precisión y repetibilidad para garantizar resultados consistentes y confiables entre diferentes muestras y operadores.
- Independencia del tipo celular y la morfología para analizar con precisión poblaciones celulares diversas y complejas.
- Salida exhaustiva de datos que incluye concentración celular, distribución de tamaño y viabilidad para obtener conocimientos más profundos.
- Flujo de trabajo eficiente y simplificado para minimizar los pasos manuales y ofrecer un tiempo más rápido hasta la obtención del resultado.
- Integridad y trazabilidad avanzadas de datos para respaldar la gestión segura de datos y el cumplimiento normativo.
- Operación rentable al reducir la dependencia de consumibles desechables para lograr ahorros a largo plazo.
Engineered for precision and efficiency, the Esco ACC Series Automatic Cell Counting Analyzer delivers a next-generation solution for accurate and reliable cell analysis.By integrating the gold-standard Coulter principle with advanced image analysis, the ACC Series provides objective, repeatable, and high-accuracy results independent of cell type or operator variability. Designed for applications in cell therapy, biopharmaceuticals, and advanced research, it enables streamlined workflows, reduces operational costs, and supports compliance-ready data management.
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Esco ACC Series Automated Cell Counting Analyzer
Specifications:
• Coulter principle-based cell counting with electrical resistance detection
• Particle size detection down to 3 µm
• Coefficient of variation (CV) as low as <5% for high repeatability
• Integrated imaging for cell viability and morphology analysis (ACC-200/300)
• Reusable microfluidic counting chip, no disposable slides required
• Compatible with common buffers and media (e.g., PBS, RPMI-1640, DMEM).
A cell counter is used to measure cell concentration, size, and viability, which are essential parameters for ensuring accuracy and consistency in research, biopharmaceutical production, and cell therapy applications.
Manual counting is time-consuming and subject to operator variability, while automated cell counters provide faster, more consistent, and reproducible results.
The Coulter principle measures changes in electrical resistance as cells pass through a micro-aperture, enabling accurate determination of cell concentration and true cell volume.
Yes, it can analyze a wide range of cell types, including primary cells, immune cells, and mixed populations, regardless of shape or optical properties.
Yes, selected models support viability analysis using staining methods such as Trypan blue to differentiate live and dead cells.
High-performance systems can achieve a coefficient variation (CV) as low as <5%, ensuring excellent accuracy and repeatability.
Some systems use disposable slides, while others utilize reusable microfluidic chips to significantly reduce long-term consumable costs.
Results are typically available within seconds after sample loading, depending on the workflow and configuration.
Yes, advanced systems support features such as user access control, audit trails, and electronic signatures to comply with regulations like 21 CFR Part 11.
It is widely used in cell therapy, biopharmaceutical development, vaccine production, stem cell research, and general laboratory applications.