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Class III Biological Safety Cabinet

ProductsBiological Safety Cabinet › Class III BSC

Class III BSC Airflow Diagram

The Class III biological safety cabinet provides an absolute level of safety, which cannot be attained with Class I and Class II cabinets. All Class III cabinets are usually made of welded metal construction and are designed to be gas tight and work is performed through glove ports in the front of the cabinet. During routine operation, negative pressure relative to the ambient environment is maintained within the cabinet which provides an additional fail-safe mechanism in case physical containment is compromised.

On all Class III cabinets, exhaust air is HEPA-filtered and incinerated. Materials are transferred into the cabinet using a pass-through unit installed at the side of the work area.

Class III cabinets usually exhaust air back to the laboratory; however, air may also be exhausted via a dedicated ductwork system to the external environment. When a dedicated ductwork system is employed, they are also suitable for work employing toxic chemicals as an adjunct to microbiological processes.

Must-have features to consider:

  • Dual exhaust ULPA filters provides better protection than single-stage designs
  • User-friendly control system
  • Single piece, leak-tested Neoprene™ gauntlets to guarantee maximum protection.
  • Integrated pass-through with interlocking doors permits materials transfer without risk of environmental contamination.
  • Angled cabinet front ensures a comfortable working posture.
  • Magnehelic gauge mounted on the rear of work zone for easy monitoring
  • Audible and visual alarms to notify user of unsafe condition
  • Isocide™ powder coat that inhibits microbial growth

Sentinel™ Silver Microprocessor Controller

Sentinel™ Silver Microprocessor Controller has one-line LCD screen for display of airflow status and time. There are soft touch keys for fan, lamp, socket, and UV lamp. The cabinet will signal audible and visual alarms during unwanted events.

Sentinel™ Gold Microprocessor Controller

Sentinel™ Gold Microprocessor Controller has four-line LCD screen for simultaneous display of airflow status, airflow velocity, socket, sash, cabinet model, and time. There are soft touch keys for blower, light, and UV lamp. The cabinet will signal audible and visual alarms during unwanted events.

HMI Control System

HMI Control System  supervises all functions and monitors cabinet performance in real time. It has a large graphical LCD to illustrate isolator operating parameters. Alarm package is available for users with more sophisticated requirements.

Airstream® Class III Biological Safety Cabinet AC3-4B
Airstream® Class III Biological Safety Cabinet


  • Dual exhaust ULPA Filter
  • Negative pressure work zone
  • Monitored by a Magnehelic™ gauge
  • Sentinel™ Silver Microprocessor controller
  • Single piece, leak-tested Neoprene™ gauntlets
  • Ergonomically angled front
  • Available sizes: 4 ft, 5 ft, and 6 ft
Containment Barrier Isolators (CBI)


  • Double-filtered exhaust air via ULPA filters
  • Single-piece and leak-tested glove assemblies for maximum protection
  • Fully welded stainless steel 316L (internal chambers) and 304 (external housing)
  • Suitable for handling Biosafety Levels 1 to 4
  • Available sizes: 4ft, 5ft, and 6ft.
Streamline® Containment Isolator - Class III


  • ISO Class 3 work zone
  • Superior operator protection for cytotoxic drug handling
  • Fast purging time
  • Motorized height stand
  • Suitable for cytotoxic drug handling
  • Available sizes: 4ft and 6ft
Turbulent Flow Aseptic Isolator (TFAI)™


  • Automated airflow and pressure control
  • LED lamps for superior illumination
  • Oval-shaped glove ports to maximize arm movement
  • Hydraulic support frame legs for operator comfort
  • Suitable for hazardous or non-hazardous drug handling
  • Available sizes: 4ft, 5ft, and 6ft.

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