Esco Stainless Steel Weighing Chamber at Beximco Pharmaceuticals Ltd.
Esco Pharma completes Esco Groups’ Life Sciences expertise in Biocontainment by providing cGMP Flowhoods running on HMI/PLCs with 21 Cfr part 11 compliance designed as Class @ A2 Biological Safety Cabinets. As an option these can be tested during IOQ with KI Discus Containment testing to EN 12469 standards. In this application our flowhood was designed with a downflow velocity of 0.45 m/s and cooling coils to maintain temperature at 21ËšC ±2Ëš. In addition, a dehumidification unit maintains <20% RH for weighing and dispensing of hygroscopic powders.
Figure 1. Class II Type B2 Biological Safety Cabinet (B2 Weighing Chamber)
Esco Product Information:
ITEM CODE: 2010861
General Specification, Labculture Class II, Type B2 (Total Exhaust) Biological Safety Cabinets | ||
Model | LB2-5B_ with SPL-5A0 | |
External Dimensions (WxDxH) | 1725 x 852 x 1795 mm 68.0” x 33.5” x 70.6”) | |
Internal/Work Area Dimensions (WxDxH) | 1570 x 623 x 900 mm (61.8” x 24.5” x 35”) | |
Usable Work Area | 0.75 m² | |
Tested Opening | 254 mm (10”) | |
Certification Exhaust | Volume | 1016 m³/h (588 cfm) |
Pressure | 375 Pa/1.5 in H20 | |
Concurrent Balance Exhaust Value* | Volume | 1853 m /h (1091 cfm) |
Pressure | 550 Pa /2.2 in H O2 | |
Downflow ULPA Filter Typical Efficiency | >99.999% for particle size between 0.1 to 0.3 microns, per IEST-RP-CC001.3 |
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Exhaust HEPA Filter Typical Efficiency | >99.99% at 0.3 microns | |
Fluorescent Lamp | >1400 Lux (>130 foot-candles) | |
Cabinet Construction | Main Body | Stainless Steel 304, 4B Finish. Walls: 1.2 mm(0.05")/18 gauge |
Work Zone | Stainless Steel 304, 4B Finish. Tray: 1.5mm(0.06")/16 gauge. Walls: 1.2 mm(0.05")/18 gauge | |
Electrical Rating | Power rating: 1 | 220-240 VAC, 50 Hz, 1ø |
Power rating: 2 | 110-130 VAC, 60 Hz, 1 ø | |
Power rating: 3 | 220-240 VAC, 60 Hz, 1 ø | |
Power rating: 7 | 100 VAC, 50/60 Hz, 1ø |
Figure 2. Flow Hood (A2 Weighing Chamber)
Esco Product Information:
ITEM CODE: 2021146
Product Unit | Flowhood | |
Airflow Class | ISO Class 2 | |
External Dimensions (WxDxH) | 1600 x 1240 x 2412 mm (63.0” x 48.8” x 95.0”) | |
Internal Work Area Dimensions (WxDxH) | 1500 x 750 x 900 mm (61.8” x 24.5” x 35”) | |
Material of Construction | SS 304 | |
Control Type | SIEMENS PLC, SIEMENS HMI, ASHCROFT Pressure Differential Transmitter (Closed Loop) |
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Chamber Condition | RH 20 ± 10% 20Ëš ± 2ËšC (DWYRER RH CONTROL) | |
Filter Stages | G4-H14 | |
Airflow Velocity | 0.45 m/s ± 20% (150 from diffuser) | |
Sound Level | < 65 dBA (300 mm in front of the unit) | |
Light Level | >600 Lux (From Working table) | |
Power Supply | 230V, 50 Hz, 1 Ph | |
Dehumidifier | Process rated Airflow 300 CMH, 200 Pa |