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Esco Stainless Steel Weighing Chamber at Beximco Pharmaceuticals Ltd.


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Esco Pharma completes Esco Groups’ Life Sciences expertise in Biocontainment by providing cGMP Flowhoods running on HMI/PLCs with 21 Cfr part 11 compliance designed as Class @ A2 Biological Safety Cabinets. As an option these can be tested during IOQ with KI Discus Containment testing to EN 12469 standards. In this application our flowhood was designed with a downflow velocity of 0.45 m/s and cooling coils to maintain temperature at 21ËšC ±2Ëš. In addition, a dehumidification unit maintains <20% RH for weighing and dispensing of hygroscopic powders.

 

Class II Type B2 Biological Safety Cabinet (B2 Weighing Chamber)

Figure 1. Class II Type B2 Biological Safety Cabinet (B2 Weighing Chamber)

Esco Product Information:

ITEM CODE: 2010861

General Specification, Labculture Class II, Type B2 (Total Exhaust) Biological Safety Cabinets
Model LB2-5B_ with SPL-5A0
External Dimensions (WxDxH) 1725 x 852 x 1795 mm 68.0” x 33.5” x 70.6”)
Internal/Work Area Dimensions (WxDxH) 1570 x 623 x 900 mm (61.8” x 24.5” x 35”)
Usable Work Area 0.75 m²
Tested Opening 254 mm (10”)
Certification Exhaust Volume 1016 m³/h (588 cfm)
Pressure 375 Pa/1.5 in H20
Concurrent Balance Exhaust Value* Volume 1853 m /h (1091 cfm)
Pressure 550 Pa /2.2 in H O2
Downflow ULPA Filter Typical Efficiency >99.999% for particle size between 0.1 to 0.3 microns,
per IEST-RP-CC001.3
Exhaust HEPA Filter Typical Efficiency >99.99% at 0.3 microns
Fluorescent Lamp >1400 Lux (>130 foot-candles)
Cabinet Construction Main Body Stainless Steel 304, 4B Finish. Walls: 1.2 mm(0.05")/18 gauge
Work Zone Stainless Steel 304, 4B Finish. Tray: 1.5mm(0.06")/16 gauge. Walls: 1.2 mm(0.05")/18 gauge
Electrical Rating Power rating: 1 220-240 VAC, 50 Hz, 1ø
Power rating: 2 110-130 VAC, 60 Hz, 1 ø
Power rating: 3 220-240 VAC, 60 Hz, 1 ø
Power rating: 7 100 VAC, 50/60 Hz, 1ø

 

Flow Hood (A2 Weighing Chamber)

Figure 2. Flow Hood (A2 Weighing Chamber)

Esco Product Information:

ITEM CODE: 2021146

Product Unit Flowhood
Airflow Class ISO Class 2
External Dimensions (WxDxH) 1600 x 1240 x 2412 mm (63.0” x 48.8” x 95.0”)
Internal Work Area Dimensions (WxDxH) 1500 x 750 x 900 mm (61.8” x 24.5” x 35”)
Material of Construction SS 304
Control Type SIEMENS PLC, SIEMENS HMI, ASHCROFT
Pressure Differential Transmitter (Closed Loop)
Chamber Condition RH 20 ± 10% 20Ëš ± 2ËšC (DWYRER RH CONTROL)
Filter Stages G4-H14
Airflow Velocity 0.45 m/s ± 20% (150 from diffuser)
Sound Level < 65 dBA (300 mm in front of the unit)
Light Level >600 Lux (From Working table)
Power Supply 230V, 50 Hz, 1 Ph
Dehumidifier Process rated Airflow 300 CMH, 200 Pa