Redefining Cell Counting Accuracy with Esco ACC Series
Imagine making critical decisions based on inconsistent cell counting data. In fields like cell therapy, biopharmaceutical development, and advanced research, even the smallest inaccuracies can lead to significant consequences. Every cell matters, and precision is everything.
Yet, many laboratories still rely on traditional methods that struggle to keep up with modern demands. Manual counting is time-consuming and highly dependent on operator judgment. Conventional image-based analyzers, on the other hand, can be influenced by cell shape, refractive index, and sample conditions, making them unreliable for complex or heterogeneous samples. So how can laboratories overcome these limitations?
A New Standard in Cell Counting
The Esco ACC Series Automated Cell Counting Analyzer introduces a next-generation solution by combining the proven Coulter principle with advanced image analysis. Unlike traditional methods, the Coulter principle measures cells based on electrical resistance. As each cell passes through a micro-aperture, it generates a voltage pulse proportional to its true volume enabling highly accurate cell counting and size determination.
This approach eliminates subjectivity and ensures results that are independent of cell morphology or operator variability.
Three Key Advantages That Set ACC Series Apart
Unbiased, Objective Results
Unbiased, Objective Results
Independent of cell type, shape, refractive index, or user technique, ensuring consistent and reliable data every time.
True Volume Measurement
True Volume Measurement
Direct measurement of hydrodynamic cell volume provides results closer to biological reality compared to image-based estimation.
Exceptional Accuracy & Repeatability
Exceptional Accuracy & Repeatability
With a coefficient of variation (CV) as low as <5%, the ACC Series delivers superior consistency across runs—even for challenging samples.
Designed for Real-World Laboratory Challenges
Modern samples are rarely simple. From PBMCs to co-culture systems, complexity is unavoidable. The ACC Series addresses this with:
- Volume-based detection independent of cell shape
- Intelligent gating for population differentiation
- Detection sensitivity down to 3 µm
- Advanced debris exclusion and de-clustering algorithms
These capabilities enable accurate analysis of heterogeneous samples while maintaining data integrity.
More Than Counting: Integrated Viability & Data Intelligence
For laboratories requiring deeper insights, the ACC-200 and ACC-300 models integrate imaging capabilities for comprehensive analysis.
Through bright-field imaging and Trypan Blue staining:
- Live cells are identified (green)
- Dead cells are detected (red)
- Cell clusters are quantified (blue)
Up to 50 images are captured during analysis, providing a complete dataset that includes count, viability, size distribution, and clustering rate. Additionally, the system ensures full data traceability:
- Automatic data storage (raw data, histograms, images)
- User access control and electronic signatures
- Optional 21 CFR Part 11 compliance for audit-ready reporting
Esco Automatic Cell Counting Analyzer
Experience accurate, efficient cell counting, regardless cell shapes and types, designed to support laboratory workflow.
*Operate with Zero Plastic Consumables per Sample
FREE TRIAL/DEMOEfficiency That Reduces Cost and Complexity
Beyond performance, the ACC Series is engineered for efficiency. By eliminating disposable counting slides and using a reusable microfluidic chip, laboratories can reduce consumable costs by over 50%.
The streamlined workflow includes:
- Prepare sample
- (Optional) Mix with dye
- Load sample
- Get results instantly
Compatible with common media such as PBS, RPMI-1640, and DMEM, the system allows direct sample loading with minimal preparation saving both time and effort.
A Complete Solution for Every Laboratory
The ACC Series offers three models tailored to different needs:
ACC-100
Precision counting specialist for accurate concentration and size analysis.
ACC-200
All-in-one platform combining counting and viability analysis for routine R&D and QC.
ACC-300
Fully automated solution with integrated staining and "Start & Add Sample" operation for high-throughput and standardized environments.
Experience the Future of Cell Counting
The Esco ACC Series Automated Cell Counting Analyzer is more than just an instrument; it is a complete solution designed to meet the evolving needs of modern laboratories. By combining accuracy, efficiency, and compliance, it empowers researchers and manufacturers to:
- Improve confidence in results
- Enhance workflow efficiency
- Reduce operational costs
- Meet regulatory requirements with ease
As science advances, so should your tools. With the ACC Series, every cell is counted with precision because every cell truly matters.